The laboratory for centrosome and cytoskeleton biology

Institute of Human Genetics, Heinrich-Heine-Universität Düsseldorf and IUF-Leibniz research institute for environmental medicine  


Univ.-Prof. Dr. Jay Gopalakrishnan Ph.D

2018:              Professor, Institute of Human Genetics, Universitätsklinikum Düsseldorf

                       Principal Investigator, Laboratory for Centrosome and Cytoskeleton Biology

                       Heinrich-Heine-Universität Düsseldorf.         


2018:              Head, Human organoids for aging research and environmental medicine

                       IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf.


2013-till date:  Group leader, Center for molecular medicine (CMMC), University of Cologne,

2012-2013:     Post-doctoral fellow, Hyman lab, Max Planck Institute-Dresden

2006-2012:     Post-doctoral fellow, Department of cell biology, Harvard Medical School,

                       Harvard University, Boston, USA

                       (Advisor. Prof. Tomer Avidor-Reiss)

                       (Academic mentors: Profs. Danesh Moazed, Tom Rapoport, and Tim Mitchison)

2001-2004:     Ph.D. student, Technical University of Berlin. Berlin, Germany

1998-2000:     M. S (by research), in chemical engineering,

                       Indian Institute of Technology, Chennai, India

1994-1998:    Bachelor in pharmacology and pharmaceutical chemistry

                      Madras Medical College, Chennai, India

Research Interest:  Biochemistry of centrosomes and cilia. Human organoids to study human biology and to reduce the usage of laboratory animals.

Marco Gottardo Ph.D

Post-doctoral researcher (Alexander Von Humboldt awardee)

Research Interest:  Mechanisms of centriole architectures and electron microscopy




Elke Gabriel Ph.D

(Post-doctoral researcher)

Research Interest:  Stem cells, tissue engineering, brain organoids and microcephaly



Arul Mariappan Ph.D

(Post-doctoral researcher)

Research Interest:  Centrosome amplification in cancers and super-resolution microscopy






Constanze Uhlmann

Guest student from Neurosurgery/IUF (Fritsche and Kahlert lab)

Research Interest:  Glioblastoma multiforme


Gladiola Goranci-Buzhala

(Ph.D student)

Research Interest:  Cilia checkpoint in glioblastoma and brain organoids



Anand Ramani

(Post-doctoral researcher)

Research Interest:  Mechanisms that build functional centrosomes







Robin Gutsche

(Master's student)

Research Interest:  Neurotropic viral infections in brain organoids



Inken Hacheney

(Technical assistant and administration)

Research Interest:  Everything that makes lab running well and cell culture


Lab 2018

Lab 2017

Lab 2017